PerkinElmer

天霁彩票网:CNS

OF

二元彩票网 www.mwbxj.com

CNS research seeks to advance treatment for central nervous system disorders through the discovery and quantitation of biomarkers, mechanisms, and drug targets. Our broad range of CNS products meets all the needs of in vitro, in situ, and in vivo central nervous system research.

We offer biomarker detection kits with AlphaLISA? and LANCE? TR-FRET technology, cellular and in vivo imaging systems, and tissue pathology solutions to assess mechanisms of CNS disease in biochemical, cellular, tissue, and animal models. We also provide target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes.

Applications for our CNS products include:

  • Measuring biomarkers of CNS disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types with our fast, pre-validated kits
  • Studying targeted binding using our radiolabeled ligands and steroids
  • Quantitating biomarkers in tissue samples with our industry-leading immunohistochemistry products
  • CNS research in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Performing phenotypic analysis with our high content screening solutions

Our CNS products are also well suited for CNS research in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Gain precise insight on disease biomarkers like phospho-tau, Ab42/Ab40, vimentin, and frataxin, as well as relevant receptors such as dopamine DA1R/DA2R.

  • 产品与服务

  • 资源,活动及更多信息

缩小结果
产品类型
  • Reagents (157)
  • Accessories (34)
  • Software and Informatics (7)
  • Consumables (2)
应用
  • Drug Discovery & Development (46)
  • In situ hybridization (ISH) (23)
  • Immunohistochemistry (IHC) (23)
  • Protein Analysis & Detection (16)
  • Molecular Biology (14)
  • cAMP (11)
检测点(200-50,000)
  • 500 (10)
  • 5000 (5)
  • 10000 (5)
检测目标
  • Aβ40 (3)
  • BDNF (2)
  • Frataxin (2)
  • TDP-43 (2)
  • GAD67 (2)
  • Aβ1-40 (2)
  • Aβ42 (1)
  • EPO (1)
  • Aβ1-x (1)
检测目标类
  • GPCR (80)
  • Protein (9)
  • Peptide (6)
  • Ion channel (3)
  • Cytokine (1)
检测验证
  • Binding (72)
  • Calcium Luminescence (32)
  • cAMP (20)
  • GTPγS (19)
  • Calcium Fluorescence (16)
  • Downstream Phosphorylation (5)
  • Inositol Phosphate (3)
自动化兼容
  • Yes (16)
缓冲
  • Tricine with stabilizer and dye (12)
  • Tricine (2)
浓度
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
检测方法
  • Fluorescence (25)
  • Radiometric (15)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
  • Alpha (6)
  • Chromogenic (6)
实验类型
  • In vitro (16)
荧光基团
  • Cy3 (8)
  • Fluorescein (6)
  • TMR (5)
  • Cy5 (4)
  • Coumarin (1)
格式
  • Slides (23)
  • Microplates (16)
宿主细胞
  • CHO-K1 (65)
  • HEK293 (13)
  • 1321N1 (4)
  • L Cells (1)
  • UC11 (1)
标签位置
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
核苷酸
  • UTP (4)
  • ATP (3)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • CTP (1)
  • GTP (1)
产品品牌名称
  • Membrane Target Systems (35)
  • Operetta (29)
  • ValiScreen (15)
  • AequoScreen (14)
  • TSA (12)
  • AequoZen (12)
  • TSA Plus (12)
  • LANCE Ultra (10)
  • Opera Phenix (7)
  • EasyTide (7)
  • cAMPZen (7)
  • AlphaLISA (6)
  • NEN Radiochemicals (6)
  • NEN (2)
  • Ancillary Products (2)
放射性核素
  • 33P (12)
  • 35S (2)
  • 3H (1)
放射性同位素
  • P-33 (12)
  • S-35 (2)
  • H-3 (1)
受体类型
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Opioid (11)
  • Galanin (10)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • Neurotensin (4)
  • GABA (4)
  • Nicotinic (4)
  • Tachykinin (1)
目标种
  • Human (16)
治疗领域
  • Central Nervous System (87)
  • Inflammation (51)
  • Cardiovascular (37)
  • Gastrointestinal (31)
  • Metabolic (30)
  • Pain (21)
  • Diabetes (10)
  • Angiogenesis (9)
  • CNS & Neurologic (1)
  • Obesity (1)
体积
  • 0-50 (1)
体积容量
  • 150 μL (2)

"CNS" 1-50200 产品与服务

每页
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA? Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.
Receptor-expressing cell lines

ValiScreen Adrenergic alpha 2A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
LANCE Detection Kit

Aβ(1-40) (human) High Specificity LANCE Ultra TR-FRET Detection Kit

The LANCE? Ultra Human Aβ(1-40) High Specificity Detection Kit is designed for detection and quantitation of human Aβ(1-40) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Receptor-expressing cell lines

Adrenergic alpha 2A AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

TSA Plus Biotin

TSA? Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: GABA B1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human GABA B1a receptor, 400 units.
TSA Cyanine 3 System

TSA Cyanine 3 System, for 50-150 Slides

TSA? Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
TSA Cyanine 3 System/Cyanine 5 System

TSA Plus Cyanine 3 and Cyanine 5 System

TSA? Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
AlphaLISA immunoassay kits

Amyloid β 1-42 (human) AlphaLISA Detection Kit

The AlphaLISA? immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA? tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: Galanin Gal1 (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human galanin Gal1 receptor, 400 units.

Frataxin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE??Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT5A Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2C (non edited isoform), Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
PerkinElmer

TSA Fluorescein System

TSA? fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Receptor-expressing cell lines

Cannabinoid CB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA -Plus TMR/Fluorescein System

TSA Plus Fluorescein and Tetramethylrhodamine (TMR) System

TSA? Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
PerkinElmer

Membrane Target Systems: Serotonin 5HT5a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT5a receptor, in HEK-293 cells.
Receptor-expressing cell lines

Serotonin 5-HT2C (ne) AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT6 (rat) membrane preparation

Cell membranes prepared from cells stably-transfected with rat Serotonin 5-HT6 receptor, in HEK-293 cells.
Receptor-expressing cell lines

AequoZen FroZen cells, Dopamine D2L, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

Opioid Mu (OP3), Human Recombinant, CHO-K1 cAMPZen Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
Receptor-expressing cell lines

Neurotensin NTS1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

CTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Cytidine triphosphate, labeled on the alpha phosphate group with 33P.
TSA Cyanine 5 System

TSA Cyanine 5 System, for 50-150 Slides

TSA? Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Receptor-expressing cell lines

ValiScreen Dopamine D3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Serotonin 5-HT6 AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA Coumarin System (100-300 slides)

TSA Coumarin System, for 100-300 Slides

TSA? coumarin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra coumarin in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: Cannabinoid CB1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

ValiScreen Opioid Kappa (OP2) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

AequoZen FroZen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
PerkinElmer

Membrane Target Systems: Opioid Kappa (OP2) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

Adrenergic alpha 2B AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

Serotonin 5-HT2C (edited) AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

AequoZen Frozen cells, Neurotensin NTS1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-6 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA -Plus DIG, 50-150 slides

TSA Plus DIG Evaluation Kit

TSA? Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2B (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
PerkinElmer

Anti-DNP AP Conjugate

Anti-DNP antibody conjugated to alkaline phosphatase
PerkinElmer

TSA Plus DNP (HRP)

TSA? Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.
Receptor-expressing cell lines

cAMPZen Frozen cells, Serotonin 5-HT6 Human Recombinant, 1321N1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
Receptor-expressing cell lines

cAMPZen FroZen Cells, Dopamine D1, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-2B (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2C (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

cAMPZen Frozen cells, Cannabinoid CB2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
PerkinElmer

Membrane Target Systems: Galanin Gal1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
PerkinElmer

TSA Biotin System

TSA? biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.

"CNS" 1-50200 产品与服务

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